N-acetylglutamate synthase (NAGS) (pronounced “nag S”) deficiency is a genetic disorder that can be passed down among family members. This disorder blocks or limits your body’s ability to remove ammonia (a waste product produced by your body). This leads to excess ammonia building up in your blood. At high levels, ammonia is toxic (or poisonous), especially to your brain. If left untreated, high blood ammonia levels can lead to brain damage or even death.
Symptoms of NAGS deficiency can be treated. Learn more about this proven treatment for the symptoms of NAGS deficiency. Any episode of acute hyperammonemia (high blood ammonia levels) with symptoms should be treated as a life-threatening emergency. Prompt use of all therapies necessary to lower blood ammonia levels is essential. This may require using a dialysis machine to remove ammonia.WATCH VIDEO ABOUT NAGS DEFICIENCY