CARBAGLU
Dosing and Administration
Including dosing adjustments for renal impairment
Including dosing adjustments for renal impairment
CARBAGLU® (carglumic acid) tablets for oral suspension 200mg should be initiated for the treatment of acute hyperammonemia in patients with a suspected or confirmed diagnosis of propionic acidemia (PA) or methylmalonic acidemia (MMA).1
Please refer to the Full Prescribing Information, including Instructions for Use, for complete dosage instructions.
CARBAGLU® (carglumic acid) tablets for oral suspension 200mg should be initiated as soon as the diagnosis of NAGS deficiency is suspected, which may be as soon as at birth, and managed by a physician and medical team experienced in metabolic disorders 1
Patients should understand the importance of taking CARBAGLU exactly as prescribed—the right dose at the right time—to ensure a constant amount of medicine in their bodies.
Please refer to the Full Prescribing Information, including Instructions for Use, for complete dosage instructions.
Before opening, store CARBAGLU in a refrigerator between 36°F to 46°F (2°C to 8°C) in the container it comes in.
After opening, store CARBAGLU at room temperature between 59°F to 86°F (15°C to 30°C). Do not store CARBAGLU in a refrigerator after opening.
Keep CARBAGLU tablets in a tightly closed container to protect the tablets from moisture.
Write the date the CARBAGLU tablet container is opened on the container label. Throw away any unused tablets one month after opening the tablet container. Do not use CARBAGLU tablets after the expiration date on the tablet container.
Keep CARBAGLU and all medicines out of the reach of children.
This brochure explains dosing and administration of CARBAGLU as well as provides ordering information.
Download in EnglishAlert your hospital pharmacy that
your patient requires CARBAGLU.
Send an order for CARBAGLU to
your hospital pharmacy and
specify whether it is a STAT order
(required in 6 hours or less).*
Ask your hospital pharmacy
to call the wholesale department
at Accredo at 1-877-900-9223
to place the order.
The wholesale department at
Accredo will work with your
hospital pharmacy to obtain
payment information, establish
shipping timelines, and verify
the delivery address.
The Accredo specialty
pharmacy team will follow
up in 1-2 days to help set up
patient home delivery of
CARBAGLU, if applicable.
*Delivery time frame is weather dependent and is not guaranteed.
Return policy: Unopened 5-count bottles of CARBAGLU can be returned for credit any time prior to the expiration date or up to 12 months past the expiration date.†
†Not applicable for CARBAGLU 60-count bottles. Product shipped as an emergency or STAT order is not eligible for credit unless damaged in transit. This policy covers products purchased after July 1, 2019. Unopened bottles have up to a 3-year expiration date and must be refrigerated. Other terms and conditions may apply.
Download the CARBAGLU Prescription & Enrollment Form for Accredo.
Complete the CARBAGLU Prescription & Enrollment Form and fax it to the Accredo specialty pharmacy
department at 1-888-454-8488.
A CARBAGLU specialty pharmacy representative may call to verify information and determine next steps.
In some cases, prior authorization may be necessary.
Questions? Contact a CARBAGLU specialty pharmacy representative at 1-888-454-8860.
Representatives are available 24/7 to assist you.
Resources to support your practice
CARBAGLU has been shown to normalize high plasma ammonia levels in NAGS deficiency patients.
Review clinical dataHyperammonemic crises can result in serious neurological complications and death. Clinicians must act quickly to diagnose and treat.
Identify symptoms and review diagnostic testsHelp your patients access payment assistance and online resources.
Access patient resourcesCarbaglu® (carglumic acid) tablets for oral suspension 200mg is a carbamoyl phosphate synthetase 1 (CPS 1) activator indicated in pediatric and adult patients as:
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